Rushville Republican

News

March 25, 2014

Purdue University discovery leads to Endocyte drug

Receives positive opinion from EU regulatory body

(Continued)

Ovarian cancer has one of the highest rates of folate receptor expression at about 85 percent. Approximately 80 percent of endometrial, lung and kidney cancers, and 50 percent of breast and colon cancers also express the receptor, Low said.

Leamon added that the positive opinions from the CHMP show the importance of persistence in developing cancer-fighting therapeutics, since many obstacles have been encountered and then solved along this rocky pathway to success.

“It takes a lot of resources, including time, to bring research from the laboratory to clinical trials, and then be considered for approval by national and international agencies,” Low said. “There is a strong team at Endocyte, Merck and Purdue University that has worked well together to develop new therapies for people affected by cancer.”

“It is always good news when promising new pharmaceuticals move one step closer to the market, and this is particularly gratifying because we know how hard Phil, Chris and the whole Endocyte team are working to bring vintafolide to the public where it can help people,” said Purdue University President Mitch Daniels. “This is just one of many medical advancements that Phil and other Purdue researchers are developing, and that is one reason why Purdue is investing $29 million in a new drug discovery building. We anticipate there will be many other companies like Endocyte originating from Purdue innovations.”

The drug discovery building and Low’s work are part of the Purdue Moves drug discovery initiative to translate basic research into life-changing treatments.

The CHMP positive opinions will be reviewed by the European Commission. If approved, the European Commission will grant a centralized marketing authorization with unified labeling that is valid in the 28 countries that are members of the European Union, as well as European Economic Area members Iceland, Liechtenstein and Norway. The European Commission usually issues a final legally binding decision within three months of a CHMP opinion.

Text Only
News
  • nws rv 081914 workcamp pic Workcamp still accepting applications for repairs The Group Workcamp Foundation is still accepting applications for home repairs for the 2015 summer season.During one week in the summer of 2015, hundreds of teenagers and adults will come to Rush County to perform minor home repairs for the elderly,

    August 19, 2014 1 Photo

  • nws-rv081914-guffey guilty pic Jury convicts Arlington man of aggravated battery Following a three day trial in the Rush Circuit Court, the jury found William P. Guffey, 44, of Arlington, guilty of aggravated battery, a Class B felony, battery on a law enforcement officer, a Class D felony, resisting law enforcement, a Class D fe

    August 19, 2014 1 Photo

  • Drive sober or get pulled over

    Drive sober or get pulled over

    August 19, 2014

  • Otis Gibbs returns to Indianapolis this Friday INDIANAPOLIS –Otis Gibbs, will perform this Friday, August 22 at 9 p.m. EST (doors open at 8 p.m. EST) at The H-FI in Fountain Square. Gibbs is on tour in support of his latest release “Souvenirs of a Misspent Youth”. The show marks the first time in

    August 19, 2014

  • eiffeltower pic Trip to Europe available for students and adults An opportunity to see some of Europe’s greatest attractions is right at the fingertips of several students and adults.Keith Perin (English 12), Meagan Hearne (Spanish) and Jennie Tague (Theatre/English) are traveling to Europe during spring break 201

    August 19, 2014 1 Photo

  • hea-rv081914-rush2health pic2 Rush2Health a success The Rush2Health Family Fitness Fair was very successful event with an estimated 600 in attendance and 247 registered for the ongoing Rush2Health program with the goals of increasing physical activity and improving eating habits.

    August 19, 2014 2 Photos

  • Berdia Merritt, 82 Berdia Merritt, 82, of Greensburg passed away Sunday, Aug. 17, 2014 in Indianapolis. Services are pending with Burns Funeral Home in Milroy.

    August 19, 2014

  • 1 nws-rv081514-steroid bust pic1 Pair charged following steroid bust A multi-departmental effort, culminated Tuesday resulting in the arrest of David E. Starkey, 39, and his wife Holly Starkey, 34, both of Rushville, on multiple drug related charges.According to Rushville Chief of Police Craig Tucker, a lengthy invest

    August 15, 2014 3 Photos

  • nws rv 081514 sasha Rescue dog hits the big time A local pooch has hit the big time and becoming the talk of the K-9 town.Sasha, an 8-year-old rescue dog from California, has been on television shows, commercials and now is plastered on a billboard just outside of town.“I adopted her from a pound w

    August 15, 2014 2 Photos

  • spt-rv081514-ephlin col headshot It's bowling time Hello, bowling fans! This is Jim Ephlin, from the Rushville Bowl, where all the action is going to be.The 2014-15 fall bowling season is upon us with many organizational meetings scheduled for next week.Monday Classic league will meet at Rushville Bo

    August 15, 2014 1 Photo

Featured Ads
AP Video
US Trying to Verify Video of American's Killing FBI Director Addresses Ferguson Shooting in Utah Raw: Police at Scene of St. Louis Shooting Police: 2 Calif. Boys Planned School Shooting NOLA Police Chief Retires Amid Violent Crimes Lunch Bus Delivers Meals to Kids Out of School Water Bottles Recalled for Safety Researcher Testing On-Field Concussion Scanners Rockets Fired From Gaza, in Breach of Ceasefire Raw: Japanese Military Live Fire Exercise Police, Protesters Clash in Ferguson Independent Autopsy Reveals Michael Brown Wounds Nashville Embraces Motley Crue Obama: 'Time to Listen, Not Just Shout' Lawyer: Gov. Perry Indictment a 'Nasty Attack' Raw: Russian Aid Convoy Crosses Into Ukraine Iowa Man Builds Statue of a Golfer Out of Balls Assange Gets Cryptic About Leaving Embassy in UK Raw: Building Collapse in South Africa, 9 Dead Raw: Pope Francis Meets 'Comfort Women'
Hyperlocal Search
Premier Guide
Find a business

Walking Fingers
Maps, Menus, Store hours, Coupons, and more...
Premier Guide
Parade
Magazine

Click HERE to read all your Parade favorites including Hollywood Wire, Celebrity interviews and photo galleries, Food recipes and cooking tips, Games and lots more.